A CpG island methylator phenotype in acute myeloid leukemia independent of IDH mutations and associated with a favorable outcome

Genetic changes are infrequent in acute myeloid leukemia (AML) compared to other malignancies and often involve epigenetic regulators, suggesting that an altered epigenome may underlie AML biology and outcomes. In 96 AML cases including 65 pilot samples selected for cured/not-cured, we found higher...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Leukemia
Main Authors: Kelly, Andrew D., Kroeger, Heike, Yamazaki, Jumpei, Taby, Rodolphe, Neumann, Frank, Yu, Sijia, Lee, Justin T., Patel, Bela, Li, Yuesheng, He, Rong, Liang, Shoudan, Lu, Yue, Cesaroni, Matteo, Pierce, Sherry A., Kornblau, Steven M., Bueso-Ramos, Carlos E., Ravandi, Farhad, Kantarjian, Hagop M., Jelinek, Jaroslav, Issa, Jean-Pierre J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5537054/
https://ncbi.nlm.nih.gov/pubmed/28074068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2017.12
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados