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Redirecting SR Protein Nuclear Trafficking Through An Allosteric Platform

Although phosphorylation directs serine-arginine (SR) proteins from nuclear storage speckles to the nucleoplasm for splicing function, dephosphorylation paradoxically induces similar movement raising the question of how such chemical modifications are balanced in these essential splicing factors. In...

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Vydáno v:J Mol Biol
Hlavní autoři: Aubol, Brandon E., Hailey, Kendra L., Fattet, Laurent, Jennings, Patricia A., Adams, Joseph A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5536852/
https://ncbi.nlm.nih.gov/pubmed/28576472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2017.05.022
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