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Disordered protein interactions for an ordered cellular transition: Cdc2-like kinase 1 is transported to the nucleus via its Ser–Arg protein substrate

Serine–arginine (SR) proteins are essential splicing factors that promote numerous steps associated with mRNA processing and whose biological function is tightly regulated through multi-site phosphorylation. In the nucleus, the cdc2-like kinases (CLKs) phosphorylate SR proteins on their intrinsicall...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: George, Athira, Aubol, Brandon E., Fattet, Laurent, Adams, Joseph A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6579451/
https://ncbi.nlm.nih.gov/pubmed/31064840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.008463
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