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CLK1 reorganizes the splicing factor U1-70K for early spliceosomal protein assembly
Early spliceosome assembly requires phosphorylation of U1-70K, a constituent of the U1 small nuclear ribonucleoprotein (snRNP), but it is unclear which sites are phosphorylated, and by what enzyme, and how such modification regulates function. By profiling the proteome, we found that the Cdc2-like k...
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| 發表在: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
National Academy of Sciences
2021
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8040622/ https://ncbi.nlm.nih.gov/pubmed/33811140 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2018251118 |
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