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Redirecting SR Protein Nuclear Trafficking Through An Allosteric Platform

Although phosphorylation directs serine-arginine (SR) proteins from nuclear storage speckles to the nucleoplasm for splicing function, dephosphorylation paradoxically induces similar movement raising the question of how such chemical modifications are balanced in these essential splicing factors. In...

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Detalhes bibliográficos
Publicado no:J Mol Biol
Main Authors: Aubol, Brandon E., Hailey, Kendra L., Fattet, Laurent, Jennings, Patricia A., Adams, Joseph A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5536852/
https://ncbi.nlm.nih.gov/pubmed/28576472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2017.05.022
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