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Mobilization of A Splicing Factor Through A Nuclear Kinase-Kinase Complex
The splicing of mRNA is dependent on serine-arginine (SR) proteins that are mobilized from membrane-free, nuclear speckles to the nucleoplasm by the Cdc2-like kinases (CLKs). This movement is critical for SR protein-dependent assembly of the macromolecular spliceosome. Although CLK1 facilitates such...
Gorde:
| Argitaratua izan da: | Biochem J |
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| Egile Nagusiak: | , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
2018
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6293969/ https://ncbi.nlm.nih.gov/pubmed/29335301 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BCJ20170672 |
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