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Structural insights into the catalytic mechanism of a family 18 exo-chitinase

Chitinase B (ChiB) from Serratia marcescens is a family 18 exo-chitinase whose catalytic domain has a TIM-barrel fold with a tunnel-shaped active site. We have solved structures of three ChiB complexes that reveal details of substrate binding, substrate-assisted catalysis, and product displacement....

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: van Aalten, D. M. F., Komander, D., Synstad, B., Gåseidnes, S., Peter, M. G., Eijsink, V. G. H.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The National Academy of Sciences 2001
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC55359/
https://ncbi.nlm.nih.gov/pubmed/11481469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.151103798
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