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Structural insights into the catalytic mechanism of a family 18 exo-chitinase
Chitinase B (ChiB) from Serratia marcescens is a family 18 exo-chitinase whose catalytic domain has a TIM-barrel fold with a tunnel-shaped active site. We have solved structures of three ChiB complexes that reveal details of substrate binding, substrate-assisted catalysis, and product displacement....
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The National Academy of Sciences
2001
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC55359/ https://ncbi.nlm.nih.gov/pubmed/11481469 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.151103798 |
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