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IRE-1α promotes viral infection by conferring resistance to apoptosis
The unfolded protein response (UPR) is an ancient cellular pathway that detects and alleviates protein-folding stresses. The UPR components X-box binding protein 1 (XBP1) and inositol-requiring enzyme 1α (IRE1α) promote type I interferon (IFN) responses. Here, we found that Xbp1-deficient mouse embr...
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| Publicado no: | Sci Signal |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5535312/ https://ncbi.nlm.nih.gov/pubmed/28588082 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.aai7814 |
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