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IRE1α Disruption Causes Histological Abnormality of Exocrine Tissues, Increase of Blood Glucose Level, and Decrease of Serum Immunoglobulin Level

Accumulation of unfolded proteins in the endoplasmic reticulum (ER) causes ER stress. As a cellular adaptive response to ER stress, unfolded protein response (UPR) activates molecules for the quality control of ER proteins. One enzyme that plays an important role in UPR is Inositol Requiring Enzyme-...

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Hlavní autoři: Iwawaki, Takao, Akai, Ryoko, Kohno, Kenji
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2946364/
https://ncbi.nlm.nih.gov/pubmed/20885949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0013052
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