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Function of IRE1 alpha in the placenta is essential for placental development and embryonic viability

Inositol requiring enzyme-1 (IRE1), a protein located on the endoplasmic reticulum (ER) membrane, is highly conserved from yeast to humans. This protein is activated during ER stress and induces cellular adaptive responses to the stress. In mice, IRE1α inactivation results in widespread developmenta...

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Detalhes bibliográficos
Main Authors: Iwawaki, Takao, Akai, Ryoko, Yamanaka, Shinya, Kohno, Kenji
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2757843/
https://ncbi.nlm.nih.gov/pubmed/19805353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0903775106
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