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Function of IRE1 alpha in the placenta is essential for placental development and embryonic viability
Inositol requiring enzyme-1 (IRE1), a protein located on the endoplasmic reticulum (ER) membrane, is highly conserved from yeast to humans. This protein is activated during ER stress and induces cellular adaptive responses to the stress. In mice, IRE1α inactivation results in widespread developmenta...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
National Academy of Sciences
2009
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2757843/ https://ncbi.nlm.nih.gov/pubmed/19805353 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0903775106 |
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