Role of IRE1α in podocyte proteostasis and mitochondrial health

Glomerular epithelial cell (GEC)/podocyte proteostasis is dysregulated in glomerular diseases. The unfolded protein response (UPR) is an adaptive pathway in the endoplasmic reticulum (ER) that upregulates proteostasis resources. This study characterizes mechanisms by which inositol requiring enzyme-...

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Detaylı Bibliyografya
Yayımlandı:Cell Death Discov
Asıl Yazarlar: Navarro-Betancourt, José R., Papillon, Joan, Guillemette, Julie, Iwawaki, Takao, Chung, Chen-Fang, Cybulsky, Andrey V.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2020
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7677398/
https://ncbi.nlm.nih.gov/pubmed/33298866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41420-020-00361-4
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