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Podocyte Injury and Albuminuria in Mice with Podocyte-Specific Overexpression of the Ste20-Like Kinase, SLK

SLK expression and activity are increased during kidney development and recovery from renal ischemia-reperfusion injury. In cultured cells, SLK promotes F-actin destabilization as well as apoptosis, partially via the p38 kinase pathway. To better understand the effects of SLK in vivo, a transgenic m...

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Detalhes bibliográficos
Main Authors: Cybulsky, Andrey V., Takano, Tomoko, Papillon, Joan, Guillemette, Julie, Herzenberg, Andrew M., Kennedy, Chris R. J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2966788/
https://ncbi.nlm.nih.gov/pubmed/20889563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.100263
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