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Genetic Ablation of Calcium-independent Phospholipase A(2)γ Exacerbates Glomerular Injury in Adriamycin Nephrosis in Mice
Genetic ablation of calcium-independent phospholipase A(2)γ (iPLA(2)γ) in mice results in marked damage of mitochondria and enhanced autophagy in glomerular visceral epithelial cells (GECs) or podocytes. The present study addresses the role of iPLA(2)γ in glomerular injury. In adriamycin nephrosis,...
Shranjeno v:
| izdano v: | Sci Rep |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Nature Publishing Group UK
2019
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6838178/ https://ncbi.nlm.nih.gov/pubmed/31700134 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-52834-x |
| Oznake: |
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