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Syk inhibitors in clinical development for hematological malignancies
Spleen tyrosine kinase (Syk) is a cytosolic non-receptor protein tyrosine kinase (PTK) and is mainly expressed in hematopoietic cells. Syk was recognized as a critical element in the B-cell receptor signaling pathway. Syk is also a key component in signal transduction from other immune receptors lik...
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| Publicado no: | J Hematol Oncol |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5534090/ https://ncbi.nlm.nih.gov/pubmed/28754125 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13045-017-0512-1 |
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