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Dysregulation of JAK-STAT pathway in hematological malignancies and JAK inhibitors for clinical application
JAK-STAT (Janus associated kinase-signal transducer and activator of transcription) pathway plays a critical role in transduction of extracellular signals from cytokines and growth factors involved in hematopoiesis, immune regulation, fertility, lactation, growth and embryogenesis. JAK family contai...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
BioMed Central
2013
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3776247/ https://ncbi.nlm.nih.gov/pubmed/24252238 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2050-7771-1-5 |
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