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The role of the JAK-STAT pathway and related signal cascades in telomerase activation during the development of hematologic malignancies

Telomerase, comprising a reverse transcriptase protein (TERT) and an RNA template, plays a critical role during senescence and carcinogenesis; however, the mechanisms by which telomerase is regulated remain to be elucidated. Several signaling pathways are involved in the activation of TERT at multis...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Yamada, Osamu, Kawauchi, Kiyotaka
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Landes Bioscience 2013
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3876434/
https://ncbi.nlm.nih.gov/pubmed/24416646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/jkst.25256
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