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Recent advances in the development of Aurora kinases inhibitors in hematological malignancies

Over the last two decades, since the discovery of Drosophila mutants in 1995, much effort has been made to understand Aurora kinase biology. Three mammalian subtypes have been identified thus far which include the Aurora A, B and C kinases. These regulatory proteins specifically work at the cytoskel...

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Detalhes bibliográficos
Publicado no:Ther Adv Hematol
Main Authors: Choudary, Iqra, Barr, Paul M., Friedberg, Jonathan
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4649604/
https://ncbi.nlm.nih.gov/pubmed/26622997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2040620715607415
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