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Recent advances in the development of Aurora kinases inhibitors in hematological malignancies

Over the last two decades, since the discovery of Drosophila mutants in 1995, much effort has been made to understand Aurora kinase biology. Three mammalian subtypes have been identified thus far which include the Aurora A, B and C kinases. These regulatory proteins specifically work at the cytoskel...

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Dades bibliogràfiques
Publicat a:Ther Adv Hematol
Autors principals: Choudary, Iqra, Barr, Paul M., Friedberg, Jonathan
Format: Artigo
Idioma:Inglês
Publicat: SAGE Publications 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4649604/
https://ncbi.nlm.nih.gov/pubmed/26622997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2040620715607415
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