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Recent advances in the development of p21-activated kinase inhibitors

The p21-activated kinases (PAKs) are downstream effectors of the small G-proteins of the Rac and cdc42 family and have been implicated as essential for cell proliferation and survival. Recent studies have also demonstrated the promise of PAKs as therapeutic targets in various types of cancers. The P...

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Detalhes bibliográficos
Main Authors: Coleman, Natalia, Kissil, Joseph
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3490963/
https://ncbi.nlm.nih.gov/pubmed/23162744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cl.21667
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