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Recent advances in the development of p21-activated kinase inhibitors

The p21-activated kinases (PAKs) are downstream effectors of the small G-proteins of the Rac and cdc42 family and have been implicated as essential for cell proliferation and survival. Recent studies have also demonstrated the promise of PAKs as therapeutic targets in various types of cancers. The P...

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Hlavní autoři: Coleman, Natalia, Kissil, Joseph
Médium: Artigo
Jazyk:Inglês
Vydáno: Landes Bioscience 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3490963/
https://ncbi.nlm.nih.gov/pubmed/23162744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cl.21667
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