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Development of small-molecule inhibitors of the group I p21-activated kinases, emerging therapeutic targets in cancer

The p21-activated kinases (PAKs), immediate downstream effectors of the small G-proteins of the Rac/cdc42 family, are critical mediators of signaling pathways regulating cellular behaviors and as such, have been implicated in pathological conditions including cancer. Recent studies have validated th...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Yi, Chunling, Maksimoska, Jasna, Marmorstein, Ronen, Kissil, Joseph L
פורמט: Artigo
שפה:Inglês
יצא לאור: 2010
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2897962/
https://ncbi.nlm.nih.gov/pubmed/20302846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2010.03.012
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