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Development of small-molecule inhibitors of the group I p21-activated kinases, emerging therapeutic targets in cancer
The p21-activated kinases (PAKs), immediate downstream effectors of the small G-proteins of the Rac/cdc42 family, are critical mediators of signaling pathways regulating cellular behaviors and as such, have been implicated in pathological conditions including cancer. Recent studies have validated th...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2010
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2897962/ https://ncbi.nlm.nih.gov/pubmed/20302846 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2010.03.012 |
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