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Checkpoint inhibitors in hematological malignancies

Inhibitory molecules such as PD-1, CTLA-4, LAG-3, or TIM-3 play a role to keep a balance in immune function. However, many cancers exploit such molecules to escape immune surveillance. Accumulating data support that their functions are dysregulated in lymphoid neoplasms, including plasma cell myelom...

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Bibliografske podrobnosti
izdano v:J Hematol Oncol
Main Authors: Ok, Chi Young, Young, Ken H.
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5422942/
https://ncbi.nlm.nih.gov/pubmed/28482851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13045-017-0474-3
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