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Checkpoint inhibitors in hematological malignancies
Inhibitory molecules such as PD-1, CTLA-4, LAG-3, or TIM-3 play a role to keep a balance in immune function. However, many cancers exploit such molecules to escape immune surveillance. Accumulating data support that their functions are dysregulated in lymphoid neoplasms, including plasma cell myelom...
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Publicado no: | J Hematol Oncol |
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Main Authors: | , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
BioMed Central
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5422942/ https://ncbi.nlm.nih.gov/pubmed/28482851 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13045-017-0474-3 |
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