Comprehensive Cross-Clade Characterization of Antibody-Mediated Recognition, Complement-Mediated Lysis, and Cell-Mediated Cytotoxicity of HIV-1 Envelope-Specific Antibodies toward Eradication of the HIV-1 Reservoir

Immunotherapy with passive administration of broadly neutralizing HIV-1 envelope-specific antibodies (bnAbs) in the setting of established infection in vivo has yielded mixed results. The contribution of different antibodies toward the direct elimination of infected cells is poorly understood. In th...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Mujib, Shariq, Liu, Jun, Rahman, A. K. M. Nur-ur, Schwartz, Jordan A., Bonner, Phil, Yue, Feng Yun, Ostrowski, Mario A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5533900/
https://ncbi.nlm.nih.gov/pubmed/28592534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00634-17
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