Comprehensive Cross-Clade Characterization of Antibody-Mediated Recognition, Complement-Mediated Lysis, and Cell-Mediated Cytotoxicity of HIV-1 Envelope-Specific Antibodies toward Eradication of the HIV-1 Reservoir

Immunotherapy with passive administration of broadly neutralizing HIV-1 envelope-specific antibodies (bnAbs) in the setting of established infection in vivo has yielded mixed results. The contribution of different antibodies toward the direct elimination of infected cells is poorly understood. In th...

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Dades bibliogràfiques
Publicat a:J Virol
Autors principals: Mujib, Shariq, Liu, Jun, Rahman, A. K. M. Nur-ur, Schwartz, Jordan A., Bonner, Phil, Yue, Feng Yun, Ostrowski, Mario A.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2017
Matèries:
Vaccines and Antiviral Agents
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5533900/
https://ncbi.nlm.nih.gov/pubmed/28592534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00634-17
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