Comprehensive Cross-Clade Characterization of Antibody-Mediated Recognition, Complement-Mediated Lysis, and Cell-Mediated Cytotoxicity of HIV-1 Envelope-Specific Antibodies toward Eradication of the HIV-1 Reservoir

Immunotherapy with passive administration of broadly neutralizing HIV-1 envelope-specific antibodies (bnAbs) in the setting of established infection in vivo has yielded mixed results. The contribution of different antibodies toward the direct elimination of infected cells is poorly understood. In th...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:J Virol
Κύριοι συγγραφείς: Mujib, Shariq, Liu, Jun, Rahman, A. K. M. Nur-ur, Schwartz, Jordan A., Bonner, Phil, Yue, Feng Yun, Ostrowski, Mario A.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: American Society for Microbiology 2017
Θέματα:
Vaccines and Antiviral Agents
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5533900/
https://ncbi.nlm.nih.gov/pubmed/28592534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00634-17
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