Cargando...
Deciphering the regulation of P2X4 receptor channel gating by ivermectin using Markov models
The P2X4 receptor (P2X4R) is a member of a family of purinergic channels activated by extracellular ATP through three orthosteric binding sites and allosterically regulated by ivermectin (IVM), a broad-spectrum antiparasitic agent. Treatment with IVM increases the efficacy of ATP to activate P2X4R,...
Guardado en:
| Publicado en: | PLoS Comput Biol |
|---|---|
| Autores principales: | , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Public Library of Science
2017
|
| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5533465/ https://ncbi.nlm.nih.gov/pubmed/28708827 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1005643 |
| Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|