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Dual Gating Mechanism and Function of P2X7 Receptor Channels

The ATP-gated P2X7 receptor channel (P2X7R) operates as a cytolytic and apoptotic receptor but also controls sustained cellular responses, including cell growth and proliferation. However, it has not been clarified how the same receptor mediates such opposing effects. To address this question, we ha...

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Detalhes bibliográficos
Main Authors: Khadra, Anmar, Tomić, Melanija, Yan, Zonghe, Zemkova, Hana, Sherman, Arthur, Stojilkovic, Stanko S.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3686336/
https://ncbi.nlm.nih.gov/pubmed/23790369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2013.05.006
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