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Dual Gating Mechanism and Function of P2X7 Receptor Channels
The ATP-gated P2X7 receptor channel (P2X7R) operates as a cytolytic and apoptotic receptor but also controls sustained cellular responses, including cell growth and proliferation. However, it has not been clarified how the same receptor mediates such opposing effects. To address this question, we ha...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
The Biophysical Society
2013
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3686336/ https://ncbi.nlm.nih.gov/pubmed/23790369 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2013.05.006 |
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