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Allosteric Regulation of the P2X4 Receptor Channel Pore Dilation
Allosteric modulators of ligand-gated receptor-channels induce conformational changes of the entire protein that alter potencies and efficacies for orthosteric ligands, expressed as the EC(50) and maximum current amplitude, respectively. Here we studied the influence of allostery on channel pore dil...
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| Publicado no: | Pflugers Arch |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4526220/ https://ncbi.nlm.nih.gov/pubmed/24917516 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00424-014-1546-7 |
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