Dual Gating Mechanism and Function of P2X7 Receptor Channels

The ATP-gated P2X7 receptor channel (P2X7R) operates as a cytolytic and apoptotic receptor but also controls sustained cellular responses, including cell growth and proliferation. However, it has not been clarified how the same receptor mediates such opposing effects. To address this question, we ha...

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Dades bibliogràfiques
Autors principals: Khadra, Anmar, Tomić, Melanija, Yan, Zonghe, Zemkova, Hana, Sherman, Arthur, Stojilkovic, Stanko S.
Format: Artigo
Idioma:Inglês
Publicat: The Biophysical Society 2013
Matèries:
Channels and Transporters
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3686336/
https://ncbi.nlm.nih.gov/pubmed/23790369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2013.05.006
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