1,6-Cyclophellitol Cyclosulfates: A New Class of Irreversible Glycosidase Inhibitor

[Image: see text] The essential biological roles played by glycosidases, coupled to the diverse therapeutic benefits of pharmacologically targeting these enzymes, provide considerable motivation for the development of new inhibitor classes. Cyclophellitol epoxides and aziridines are recently establi...

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Foilsithe in:ACS Cent Sci
Main Authors: Artola, Marta, Wu, Liang, Ferraz, Maria J., Kuo, Chi-Lin, Raich, Lluís, Breen, Imogen Z., Offen, Wendy A., Codée, Jeroen D. C., van der Marel, Gijsbert A., Rovira, Carme, Aerts, Johannes M. F. G., Davies, Gideon J., Overkleeft, Herman S.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Chemical Society 2017
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5532717/
https://ncbi.nlm.nih.gov/pubmed/28776021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acscentsci.7b00214
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