1,6-Cyclophellitol Cyclosulfates: A New Class of Irreversible Glycosidase Inhibitor

[Image: see text] The essential biological roles played by glycosidases, coupled to the diverse therapeutic benefits of pharmacologically targeting these enzymes, provide considerable motivation for the development of new inhibitor classes. Cyclophellitol epoxides and aziridines are recently establi...

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Pubblicato in:ACS Cent Sci
Autori principali: Artola, Marta, Wu, Liang, Ferraz, Maria J., Kuo, Chi-Lin, Raich, Lluís, Breen, Imogen Z., Offen, Wendy A., Codée, Jeroen D. C., van der Marel, Gijsbert A., Rovira, Carme, Aerts, Johannes M. F. G., Davies, Gideon J., Overkleeft, Herman S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Chemical Society 2017
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5532717/
https://ncbi.nlm.nih.gov/pubmed/28776021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acscentsci.7b00214
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