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Glucocorticoid therapy regulates podocyte motility by inhibition of Rac1

Nephrotic syndrome (NS) occurs when the glomerular filtration barrier becomes excessively permeable leading to massive proteinuria. In childhood NS, immune system dysregulation has been implicated and increasing evidence points to the central role of podocytes in the pathogenesis. Children with NS a...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: McCaffrey, James C., Webb, Nicholas J., Poolman, Toryn M., Fresquet, Maryline, Moxey, Cressida, Zeef, Leo A. H., Donaldson, Ian J., Ray, David W., Lennon, Rachel
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5532274/
https://ncbi.nlm.nih.gov/pubmed/28751734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-06810-y
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