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Oncogenic suppression of apoptosis uncovers a Rac1/JNK proliferation pathway activated by loss of Par3

Disruption of epithelial organization and loss of growth control are universal features of carcinomas, yet how these features are linked during cancer progression remains poorly understood. Cell polarity proteins control cellular and tissue organization and are emerging as important mediators of can...

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Detalhes bibliográficos
Publicado no:Oncogene
Main Authors: Archibald, Andrew, Mihai, Constantina, Macara, Ian G., McCaffrey, Luke
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4324374/
https://ncbi.nlm.nih.gov/pubmed/25109337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2014.242
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