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The Par3/aPKC interaction is essential for end bud remodeling and progenitor differentiation during mammary gland morphogenesis

Mammalian polarity proteins have been studied predominantly in cell culture systems, and little is known about their functions in vivo. To address this issue, we used a shRNA lentiviral system to manipulate gene expression in mouse mammary stem/progenitor cells. Transplantation of Par3-depleted stem...

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Hlavní autoři: McCaffrey, Luke Martin, Macara, Ian G.
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2701573/
https://ncbi.nlm.nih.gov/pubmed/19528321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1795909
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