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The Par3/aPKC interaction is essential for end bud remodeling and progenitor differentiation during mammary gland morphogenesis

Mammalian polarity proteins have been studied predominantly in cell culture systems, and little is known about their functions in vivo. To address this issue, we used a shRNA lentiviral system to manipulate gene expression in mouse mammary stem/progenitor cells. Transplantation of Par3-depleted stem...

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מידע ביבליוגרפי
Main Authors: McCaffrey, Luke Martin, Macara, Ian G.
פורמט: Artigo
שפה:Inglês
יצא לאור: Cold Spring Harbor Laboratory Press 2009
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2701573/
https://ncbi.nlm.nih.gov/pubmed/19528321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1795909
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