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Dosage-dependent role of Rac1 in podocyte injury
Activation of small GTPase Rac1 in podocytes is associated with rodent models of kidney injury and familial nephrotic syndrome. Induced Rac1 activation in podocytes in transgenic mice results in rapid transient proteinuria and foot process effacement, but not glomerular sclerosis. Thus it remains an...
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| Publicado no: | Am J Physiol Renal Physiol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4835924/ https://ncbi.nlm.nih.gov/pubmed/26792065 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00381.2015 |
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