Loss of Epithelial Membrane Protein 2 Aggravates Podocyte Injury via Upregulation of Caveolin-1

Nephrotic syndrome is a CKD defined by proteinuria with subsequent hypoalbuminemia, hyperlipidemia, and edema caused by impaired renal glomerular filtration barrier function. We previously identified mutations in epithelial membrane protein 2 (EMP2) as a monogenic cause of this disease. Here, we gen...

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Dades bibliogràfiques
Publicat a:J Am Soc Nephrol
Autors principals: Wan, Xiaoyang, Chen, Zhaohong, Choi, Won-Il, Gee, Heon Yung, Hildebrandt, Friedhelm, Zhou, Weibin
Format: Artigo
Idioma:Inglês
Publicat: American Society of Nephrology 2016
Matèries:
Basic Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4814174/
https://ncbi.nlm.nih.gov/pubmed/26264854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2014121197
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