Glucocorticoid therapy regulates podocyte motility by inhibition of Rac1

Nephrotic syndrome (NS) occurs when the glomerular filtration barrier becomes excessively permeable leading to massive proteinuria. In childhood NS, immune system dysregulation has been implicated and increasing evidence points to the central role of podocytes in the pathogenesis. Children with NS a...

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Publicado en:Sci Rep
Autores principales: McCaffrey, James C., Webb, Nicholas J., Poolman, Toryn M., Fresquet, Maryline, Moxey, Cressida, Zeef, Leo A. H., Donaldson, Ian J., Ray, David W., Lennon, Rachel
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group UK 2017
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5532274/
https://ncbi.nlm.nih.gov/pubmed/28751734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-06810-y
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