Skp2 deficiency restricts the progression and stem cell features of castration-resistant prostate cancer by destabilizing Twist

Castration-resistant prostate cancer (CRPC) remains a major clinical challenge due to the lack of effective targeted therapy for its treatment. The mechanism underlying how CRPC gains resistance towards hormone depletion and other forms of chemotherapy is poorly understood. Research on understanding...

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Bibliographic Details
Published in:Oncogene
Main Authors: Ruan, Diane, He, Jiabei, Li, Chien-Feng, Lee, Hong-Jen, Liu, Jingxuan, Lin, Hui-Kuan, Chan, Chia-Hsin
Format: Artigo
Language:Inglês
Published: 2017
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5532065/
https://ncbi.nlm.nih.gov/pubmed/28346424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2017.64
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