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Cardiotonic steroids stimulate macrophage inflammatory responses through a pathway involving CD36, TLR4, and Na/K-ATPase

OBJECTIVE: Circulating levels of cardiotonic steroids (CTS) are elevated in various chronic inflammatory conditions, but the role of CTS in inflammation remains largely unknown. We have previously shown that the CTS ouabain stimulates pro-inflammatory responses in murine macrophages. In this study,...

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Detalhes bibliográficos
Publicado no:Arterioscler Thromb Vasc Biol
Main Authors: Chen, Yiliang, Huang, Wenxin, Yang, Moua, Xin, Gang, Cui, Weiguo, Xie, Zijian, Silverstein, Roy L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5532064/
https://ncbi.nlm.nih.gov/pubmed/28619997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.117.309444
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