Mitochondrial metabolic reprogramming by CD36 signaling drives macrophage inflammatory responses

RATIONALE: A hallmark of chronic inflammatory disorders is persistence of pro-inflammatory macrophages in diseased tissues. In atherosclerosis this is associated with dyslipidemia and oxidative stress, but mechanisms linking these phenomena to macrophage activation remain incompletely understood. OB...

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Publicat a:Circ Res
Autors principals: Chen, Yiliang, Yang, Moua, Huang, Wenxin, Chen, Wenjing, Zhao, Yiqiong, Schulte, Marie L., Volberding, Peter, Gerbec, Zachary, Zimmermann, Michael T., Zeighami, Atefeh, Demos, Wendy, Zhang, Jue, Knaack, Darcy A., Smith, Brian C., Cui, Weiguo, Malarkannan, Subramaniam, Sodhi, Komal, Shapiro, Joseph I., Xie, Zijian, Sahoo, Daisy, Silverstein, Roy L.
Format: Artigo
Idioma:Inglês
Publicat: 2019
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6921463/
https://ncbi.nlm.nih.gov/pubmed/31625810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.119.315833
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