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Oxidized LDL-bound CD36 recruits a Na(+)/K(+)-ATPase-Lyn complex in macrophages that promotes atherosclerosis
One characteristic of atherosclerosis is the accumulation of lipid-laden macrophage foam cells in the arterial wall. We have previously shown that the binding of oxidized LDL (oxLDL) to the scavenger receptor CD36 activates the kinase Lyn, initiating a cascade that inhibits macrophage migration and...
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Publicado no: | Sci Signal |
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Main Authors: | , , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4852751/ https://ncbi.nlm.nih.gov/pubmed/26350901 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.aaa9623 |
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