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Cardiotonic steroids stimulate macrophage inflammatory responses through a pathway involving CD36, TLR4, and Na/K-ATPase

OBJECTIVE: Circulating levels of cardiotonic steroids (CTS) are elevated in various chronic inflammatory conditions, but the role of CTS in inflammation remains largely unknown. We have previously shown that the CTS ouabain stimulates pro-inflammatory responses in murine macrophages. In this study,...

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Vydáno v:Arterioscler Thromb Vasc Biol
Hlavní autoři: Chen, Yiliang, Huang, Wenxin, Yang, Moua, Xin, Gang, Cui, Weiguo, Xie, Zijian, Silverstein, Roy L.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5532064/
https://ncbi.nlm.nih.gov/pubmed/28619997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.117.309444
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