Crystal structure and kinetic analysis of the class B3 di-zinc metallo-β-lactamase LRA-12 from an Alaskan soil metagenome

We analyzed the kinetic properties of the metagenomic class B3 β-lactamase LRA-12, and determined its crystallographic structure in order to compare it with prevalent metallo-β-lactamases (MBLs) associated with clinical pathogens. We showed that LRA-12 confers extended-spectrum resistance on E. coli...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Rodríguez, María Margarita, Herman, Raphaël, Ghiglione, Barbara, Kerff, Frédéric, D’Amico González, Gabriela, Bouillenne, Fabrice, Galleni, Moreno, Handelsman, Jo, Charlier, Paulette, Gutkind, Gabriel, Sauvage, Eric, Power, Pablo
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5531557/
https://ncbi.nlm.nih.gov/pubmed/28750094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0182043
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados