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Carborane-based design of a potent vitamin D receptor agonist
The vitamin D nuclear receptor (VDR) is a potential target for cancer therapy. It is expressed in many tumors and its ligand shows anticancer actions. To combine these properties with the application of boron neutron capture therapy (BNCT), we design and synthesize a potent VDR agonist based on the...
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| Publicado no: | Chem Sci |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Royal Society of Chemistry
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5531031/ https://ncbi.nlm.nih.gov/pubmed/28808527 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5sc03084f |
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