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Structural analysis and biological activities of BXL0124, a gemini analog of vitamin D
Gemini analogs of calcitriol, characterized by the extension of the C21-methyl group of calcitriol with a second chain, act as agonists of the vitamin D receptor (VDR). This second side chain of gemini is accommodated in a new cavity inside the VDR created by the structural rearrangement of the prot...
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| Опубликовано в: : | J Steroid Biochem Mol Biol |
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| Главные авторы: | , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2016
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5357203/ https://ncbi.nlm.nih.gov/pubmed/27650654 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsbmb.2016.09.015 |
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