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Ionic CD3−Lck interaction regulates the initiation of T-cell receptor signaling
Antigen-triggered T-cell receptor (TCR) phosphorylation is the first signaling event in T cells to elicit adaptive immunity against invading pathogens and tumor cells. Despite its physiological importance, the underlying mechanism of TCR phosphorylation remains elusive. Here, we report a key mechani...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5530670/ https://ncbi.nlm.nih.gov/pubmed/28659468 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1701990114 |
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