Combinatorial proteomic analysis of intercellular signaling applied to the CD28 T-cell costimulatory receptor

Systematic characterization of intercellular signaling approximating the physiological conditions of stimulation that involve direct cell–cell contact is challenging. We describe a proteomic strategy to analyze physiological signaling mediated by the T-cell costimulatory receptor CD28. We identified...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Tian, Ruijun, Wang, Haopeng, Gish, Gerald D., Petsalaki, Evangelia, Pasculescu, Adrian, Shi, Yu, Mollenauer, Marianne, Bagshaw, Richard D., Yosef, Nir, Hunter, Tony, Gingras, Anne-Claude, Weiss, Arthur, Pawson, Tony
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2015
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PNAS Plus
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4386406/
https://ncbi.nlm.nih.gov/pubmed/25829543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1503286112
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