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MAK33 antibody light chain amyloid fibrils are similar to oligomeric precursors

Little structural information is available so far on amyloid fibrils consisting of immunoglobulin light chains. It is not understood which features of the primary sequence of the protein result in fibril formation. We report here MAS solid-state NMR studies to identify the structured core of κ-type...

詳細記述

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書誌詳細
出版年:PLoS One
主要な著者: Hora, Manuel, Sarkar, Riddhiman, Morris, Vanessa, Xue, Kai, Prade, Elke, Harding, Emma, Buchner, Johannes, Reif, Bernd
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5528828/
https://ncbi.nlm.nih.gov/pubmed/28746363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0181799
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