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Ubiquitin specific protease 4 positively regulates the WNT/β‐catenin signaling in colorectal cancer
β‐catenin is a key signal transducer in the canonical WNT pathway and is negatively regulated by ubiquitin‐dependent proteolysis. Through screening of various deubiquitinating enzymes (DUBs), we identified ubiquitin specific protease 4 (USP4) as a candidate for β‐catenin‐specific DUB. The effects of...
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| Izdano u: | Mol Oncol |
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| Glavni autori: | , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
John Wiley and Sons Inc.
2015
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5528720/ https://ncbi.nlm.nih.gov/pubmed/26189775 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2015.06.006 |
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