Ubiquitin-specific protease 4 controls metastatic potential through β-catenin stabilization in brain metastatic lung adenocarcinoma

Brain metastasis is the most common type of intracranial cancer and is the main cause of cancer-associated mortality. Brain metastasis mainly originates from lung cancer. Using a previously established in vitro brain metastatic model, we found that brain metastatic PC14PE6/LvBr4 cells exhibited high...

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Pubblicato in:Sci Rep
Autori principali: Hwang, Su Jin, Lee, Hye Won, Kim, Hye Ree, Lee, Hong, Shin, Chang Hoon, Yun, Sun-Il, Lee, Dong Heon, Kim, Duk-Hwan, Kim, Kyeong Kyu, Joo, Kyeung Min, Kim, Hyeon Ho
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4756316/
https://ncbi.nlm.nih.gov/pubmed/26883469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep21596
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