The tyrosine phosphatase SHP2 is required for cell transformation by the receptor tyrosine kinase mutants FIP1L1‐PDGFRα and PDGFRα D842V

Activated forms of the platelet derived growth factor receptor alpha (PDGFRα) have been described in various tumors, including FIP1L1‐PDGFRα in patients with myeloproliferative diseases associated with hypereosinophilia and the PDGFRα(D842V) mutant in gastrointestinal stromal tumors and inflammatory...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:Mol Oncol
Main Authors: Noël, Laura A., Arts, Florence A., Montano-Almendras, Carmen P., Cox, Luk, Gielen, Olga, Toffalini, Federica, Marbehant, Catherine Y., Cools, Jan, Demoulin, Jean-Baptiste
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2014
Assuntos:
Research Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5528641/
https://ncbi.nlm.nih.gov/pubmed/24618081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2014.02.003
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares